2/2/2024 0 Comments Qarc ventricles altasPretreatment position was verified with kV-kV x-rays and cone beam CT. Respiratory gating was not performed to minimize treatment time and complexity because it had minimal ITV margin gains. The use of abdominal compression was evaluated, but it did not provide ITV margin reductions, brought the stomach closer to the PTV, and thus was not used. Angles were chosen to avoid unnecessary irradiation of the right lung. Although the heart can be considered central, in both cases, the target's centroid was near the middle of the left lung. The treatments were delivered with 3 coplanar partial arcs. Radiation was delivered with a TrueBeam STx Linear Accelerator (Varian Medical Systems) using a 6-MV flattening-filter-free beam and a volumetric modulated arc therapy technique. Pretreatment quality assurance plan review was performed according to internal department guidelines for stereotactic body radiation therapy. The PTVs were prescribed 25 Gy in 1 fraction with the plan normalized so that 95% of the PTV was covered by the 25 Gy isodose. Case 2īy the RO and reviewed by the EP ( Table 1). The likelihood of clinical success with a repeat CA was deemed low given the large number of morphologies and complex substrate underlying the arrhythmias. Reviewing the ICD suggested multiple VT circuits and cycle lengths consistent with the previous electrophysiologists (EP) study. Ablation was attempted in 2017 targeting a scar on the lateral wall of the LV. The patient was on maximum tolerable amiodarone (400 mg daily). ![]() The patient underwent quintuple coronary artery bypass graft surgery (in 2004) after a myocardial infarction, and in 2013, a prophylactic ICD was placed. The patient had a significantly reduced left ventricular ejection fraction 30%, and multiple comorbidities, including coronary artery disease, type 2 diabetes mellitus, and chronic kidney disease. Reversible precipitating factors including ischemia, electrolyte imbalances, and drug interactions were ruled out in the ED. position effects).A 65-year-old man known with recurrent VT secondary to ischemic cardiomyopathy presenting to the emergency department (ED) in VT storm requiring multiple ICD shocks. To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.Īnomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database. Lyford GL, Yamagata K, Kaufmann WE, Barnes CA, Sanders LK, Copeland NG, Gilbert DJ, Jenkins NA, Lanahan AA, Worley PF.Ĭonfirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. Klebaur JE, Ostrander MM, Norton CS, Watson SJ, Akil H, Robinson TE.Īrc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites. The ability of amphetamine to evoke arc (Arg 3.1) mRNA expression in the caudate, nucleus accumbens and neocortex is modulated by environmental context. Gene Expression Annotations for this image The cerebellum is stained in the BAC mice. Our BAC data reveals expression mainly in CA3 and dentate gyrus. in hippocampus, the in situ data shows higher Arc expression in CA regions and subiculum. ![]() There are a few discrepancies between BAC data and in situ data at P7. Confirmed expression sites include MOB, olfactory tubercle, nucleus accumbens, striatum, cortex and reticular thalamic nucleus. The BAC data is consistent with both literature and BGEM in situ data in general. If you change detail scale, new detail will load. ![]() A new window will pop up displaying selected detail.Read gene expression annotations for this image.UCSC Genome Browser for this BAC Address: RP23-429N15.Get this mouse from MMRRC: STOCK Tg(Arc-EGFP)EL194Gsat/Mmucd: Details, Order.Activity regulated cytoskeletal-associated proteinĭouble-click anywhere in the image below.
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